Zach Bush MD and COVID-19

24 April 2021

So a good friend of mine who studies holistic medicine suggested I check out Zach Bush MD. So I've been watching some videos. This was more or less my response.

He's a smart dude.

In particular, I watched the "innate immune system" video from his website, which seems to encourage us all to get COVID so that the human race (or perhaps the global virome can evolve) can evolve. And ultimately, I think he's pulling a fast least as far as COVID-19 goes.

So, in the first half of the video, he does a great job of explaining how our immune system works (at least to my knowledge). Viruses enter our bodies and our immune systems use existing defenses to keep the virus at bay or they develop new defenses. And we do this all the time. So far, so good. But then he pulls his first fast one. He says that the adaptation represents an "instability" in our innate immune system, but this is just because our immune system hasn't developed a response to that particular virus yet. Once it has, that response floats around with the other 10^15 responses as part of our innate immune system. So the notion of "innate" is a moving target for him. "Innate" only means that the immune system already has a response. For him, once we develop a response to a new flu variant (our "adaptive rsponse"), it is part of our innate immune system. Our entire immune system/virome has evolved and continues to evolve in this way. What I'm trying to say (I think!) is that he is creating a false binary between innate and adaptive that makes it sound like the innate is something ancestral and pure.

The second fast one comes with his dismissal of the vaccine. First he is telling us that the adaptive response to new viruses provides our inner virome with new genetic information (totally agree). But then he doubts that there are viruses we are not prepared for. "What are the chances that your innate immune system would encounter a virus is wasn't prepared for?" By his own numbers, there are only 10^15 inside us and 3*10^31 in the environment around us (soil, air, sea). That is a huge number of viruses never encountered, magnitudes more than are inside us. So it's actually highly likely that we would encounter a new virus...and it probably happens all the time.

That's where we get to number three. Most of the new viruses we encounter don't pose any risk. But some do. Some, like SARS-CoV-19, successfully exploit our cellular machinery by convincing it to produce even more copies of the virus. So some viruses are more dangerous than others. Zach Bush MD seems to consider all viruses to be equivalent in their relationship with our bodies. This is a false equivalence. The implication of this equivalence is that we should just let those whose immune systems cannot protect themselves die as part of the evolutionary process. Fine to say until it's people you know whose lives are threatened.

The fourth fast one is that he speaks as though the effects of the vaccine are ultimately different from the effects of encountering the virus in the wild. In my view, this is not the case. The whole point of a vaccine is to introduce the viral information in a safe way (inert viral DNA or mRNA) that prompts the innate immune system to launch an adaptive response that will create the antibodies/antigens needed in case the body encounters a live and vicious version of the virus. In essence, all a vaccine does is consciously and deliberately give our immune systems the viromic information it needs to fight a virus rather than wait for a chance encounter. Reaching herd immunity through vaccination just reflects the processing of new information and helps the virome stabilize.

Then he tosses in the falsehood that COVID-19 is rewriting our genome, but that's another discussion for another time.

So, while I find his position a bit disingenuous, I actually agree with a lot of what he is saying. His basic message in the videos I've watched seems to be that if we are healthier and live healthier lives we won't get as sick and that we can live healthier lives by cleaning up our environment. He uses much more complex and technical terms, but I think bottom-line that is what he is saying.

Anyway, that's what I think after a few hours of listening to him. Maybe you have a different take, reader?

Shock G and the eternal underwater

23 April 2021

Shock G is now underwater riming on a permanent basis. RIP.

The loss of Shock G today has really touched me. Obviously, the man was a creative force and hip hop innovator. First and foremost, he and the rest of Digital Underground perpetuated the magic that is Parliament-Funkadelic. In doing so, they moved California hip hop beyond basic gangster rap, moving the medium into realms of lyrical creativity still to be matched. Second, Digital Underground was Oakland Blank Panther conscious, particularly on Sons of the P. Third, they are just plain funky. Other people are thrilled that they basically discovered and made Tupac, but I'll DU any old day. (There's much more, of course, but my daughter is calling me away to experiment with TNT in Minecraft.)

But I'm also touched because Digital Underground was more or less synonymous with my time in San Francisco. I saw Shock G dance The Humpty Dance at a club South of Market. I'm sure I sat on BART listening to Sex Packets on a CD Walkman. Quite simply, DU is inseparable from my SF experience. More frighteningly, Shock G was just a few years older than I am. And when your idols are the same age and move on it brings mortality to the forefront.

Wish I could share some Heartbeat Props.

Fresh falling leaves and affect

23 April 2021

I've been trying to experience a more open systems, flatly ontological life lately. Inspired by the summary of ideas in Arturo Escobar's Designs for the Pluriverse and Jane Bennett's Vibrant Matter, I read some Thoreau, in particular his chapter entitled "Ktaadn". "Ktaadn" traces Thoreau's journey away from civilization to a transcendental moment of unity with the Wild in the clouds atop Mount Katahdin in the Maine wilderness. The underlying notion is that there is a blurry line between civilization and the self and the essence of things, their thing-power or noumena. That is there is existence beyond our linguistic apparatuses and our consciousness of self that shapes our selfness through its engagement with that selfsame selfness. This is affect.

Walking through the woods (the Wild?) on my way to work this morning, I experienced something that seemed to capture my mood. My attention was snapped away from its thoughts by a crack and a downward whirling of a sprig of three elm(?) leaves perhaps too large and weighty for this early in spring. As the trio caught on some bare branch, I found myself thinking that the rotor-spinning descent was simultaneously a celebratory moment of beauty and a languid contemplation of maturation.

Transition design and gender swapping

20 April 2021

Lately I've been reading Arturo Escobar's Designs for the Pluriverse. The book strives to compile and organize the theory around autonomous designing across different onto-epistemological worlds in the interest of transitioning to a sustainable, convivial future. The basic idea is that we simultaneously create and understand our world through making it. Thus, different understandings of the world lead to different design outcomes (materially, socially, politically, economically, and so forth). And vice versa. One minor example would be designing our drinking instruments with handles. By changing the way we hold our cups, we change the way we use them. With handles, it is easier to manage hot drinks, like tea, and thus leads us to think of cups a holders of hot liquids rather than just cool liquids. It might also lead to new cultural practices of distinction, like sticking your pinky finger out when you lift your cup. More significantly(?), designing our economic production and distribution around markets has led us to think of ourselves as rational economic actors in competition with each other and to embrace cultural practices of competitive exchange and maximizing consumption.

The book is home to a wonderful set of ideas, though I am getting a bit frustrated with it level of abstraction, which will hopefully be resolved in the next chapter or two I read. One of the ideas that has captured my imagination this week is one of the principles of transition design. Transition design is a (Western, designer-centric) approach to designing the transition to a new future. One of its principles, according to Escobar, is that the approach assumes that we are already undergoing a transition...whether we like it or not. Our climate is changing. Capitalism is once again approaching its limits and revealing its contradictions. Technology is creating new ways of connecting and weakening others. And so on. But transition design indicates that our future can o in many different directions. In one simplified set of trajectories, we can plummet into civilization collapse, wallow in incremental actions that perpetuate and prolong the crisis, or embrace a more convivial future. But the transition design thinkers appear to be optimistic. Perhaps that is necessary to achieve the transition: optimism as a design output. Either way, it's refreshing.

And my daughters gave me further cause for optimism this morning. One daughter was talking about how boys from her class were already designing their Halloween plague doctor costumes and how she was thinking about going as Harry Potter. My other daughter responded enthusiastically with "Gender-swap Harry Potter!" There was no questioning the propriety of a girl dressing as a boy. There was the assumption, I think, that gender exploration was a positive form of play. The 21st century may not be so bad after all!

Seasons and Sounds

03 March 2021

Thanks to COVID, I have spent much more time this year hiking in Bukhansan National Park. I've gone hiking at least once a week for the last year, three times a week when the gym has been closed. It's become familiar enough that I know what lies around the next corner, which rocks are risky, and what names I've given to the different stretches of the trails. It has also allowed me to observe the slow transition between seasons and of seasons.

Over the last two weeks I have been struck by the emerging sounds of spring. One of the beautiful aspects of hiking in the winter, especially after it has snowed, is the dramatic silence. There are no leaves rustling. If there is snow, it mutes any sounds that do emerge. So the drilling of woodpeckers stands out and makes identifying their location simple. It's a peaceful experience.

But spring is coming. And the sounds are changing. Last week was quite warm and birds were singing their welcome to spring. New birdsong reverberated off the bare rocks and through the empty branches. The coming spring was being heralded. Today was even noisier, but it was not due to the birds. Over the last week, the snow and ice that had blanketed the streams and muffled the rippling water had melted. In their place, newly melted snow from a late winter storm was rushing over the rocks with a fury not heard since the fall. The sound, though boisterous, was almost intrusive.

Spring begins to sing.

Winter break and new starts

27 January 2021

Let me first note that what I am about to relate may simply be a new form of procrastination.

I spent a good chunk of my morning moving bookcases around to make some books more accessible and to open up a little more space. Yesterday I took down a delicately drawn map of Yangon, which had been obscured behind a wardrobe. I also conducted a preliminary reorganization of some of my books to clear away piles designed to designate immanent reading material that were blocking other rows of books. It had been a turbulent example of thought in action, though in truth more potential than actual action.

The details aren't really important. What I believe they represent may be. I believe my actions of the last several days have been marking a transition from one phase to another. I recently applied for full tenure, and there is no reason not to expect it to be granted. Korea's system is fairly transparent and quantitative, and I have far surpassed the minimum requirements to acquire tenure. I presume the security of tenure is starting to sink in and birth the freedom of thought and exploration that it is designed to do.

Over the past decade, I have focused my energies on exploring the export of Korean new towns and apartment complexes overseas. I was even fortunate to receive a large grant from Korea's National Research Foundation that allowed me to learn about Myanmar and Vietnam in particular and research more generally. The three-year grant was from 2015 to 2018, but the research and paper writing lingered as I tried to clean up many of the loose ends. There are at least a half dozen papers my colleague and I wrote that never made it past their initial draft or presentation. I felt compelled to complete them, to ensure that the effort was not wasted. But two days ago I finally gave myself permission to let them go and close up shop. I may go back to them at some point or in some form, but I am no longer obliged to do so.

Rather, I can look forward to a new project or two. Two projects have been simmering away for a couple of years, while others have been cooling on the back burner. The first project is converting my Introduction to Development course into a book (of some sort). The second is---at least initially---a more radical departure that will take time to come to fruition. I want to explore the role of systems theory in urban history and theory and link this to artificial intelligence. The fundamental premise is that our societies are moving inextricably toward AI-driven policy making and operation. Since AI is based ultimately on cybernetics and systems theory, we need to come to grips with this history in urban planning. Hopefully, something useful will emerge.

Trump and COVID success

26 January 2021

As we pass 400,000 deaths in the US due to COVID-19, this is your friendly reminder that a bit less than a year ago, Trump outrageously tried to lower expectations by claiming that he would consider his government successful if it kept COVID-19 deaths below 200,000.

Trump and impermanence

8 January 2021

Like many, I have spent the last several days doomscrolling, reading political journalism, and listening to Congressional speeches in an effort to make sense of the assault on the Capitol building. It's not that I'm surprised that Trump's tenure has brought us to this point. Rather, it reflects my worry about the future of my country.

My thought is that America's democratic tradition will hold fast and secure a reasonable form of government for the foreseeable future. Much of this is contingent on how well the Biden administration can deradicalize the far right. In my view this will require a much more equitable distribution of wealth, and I do not know that I trust Biden's crew to deliver on this. If they don't, problems are likely to worsen. If we do, there is hope.

But I am mainly writing to offer my overly simplistic interpretation of Trump's act of sedition. I see it as the dramatic, climactic season finale of the Trump (shit)show. The Presidency has provided us with a never ending series of dramatic moments, plot twists, and characters driven by a narrative of good versus evil for both sides of the political fence. So it's appropriate that the season finale would culminate in an apocalyptic showdown between the forces of good and evil.

My suggestion is that---despite the very real negative consequences of Trump's administration---it has engaged Americans, if not the world, in a reality TV show underscored by the same fundamental themes that drive the success of the Star Wars franchise and similar vehicles. And I believe my suggestion that it really was "just" a season finale is borne by Trump's message today that clearly stated that there would be an orderly transition to a new administration and that despite everyone's disappointment this is just the beginning.

Stay tuned for Season 2.